THE NEUROPSYCHOLOGICAL REPERCUSSIONS OF CELIAC DISEASE IN CHILDHOOD: A REVIEW LITERATURE INTEGRATIVE
Palavras-chave:
doença celíaca, infância, dieta livre de glúten, distúrbios psiquiátricosResumo
CELIAC DISEASE IS AN AUTOIMMUNE DISEASE CAUSED BY INTOLERANCE TO GLUTEN, A PROTEIN FOUND IN WHEAT, OATS, BARLEY, RYE AND THEIR DERIVATIVES, CAUSING VILLOUS ATROPHY OF THE INTESTINAL MUCOSA. THE DIAGNOSIS OF CELIAC DISEASE IS BASED ON A COMBINATION OF FINDINGS FROM THE PATIENT'S CLINICAL HISTORY AND SPECIFIC TESTS. PSYCHIATRIC DISORDERS HAVE BEEN FREQUENTLY REPORTED IN PATIENTS WITH CELIAC DISEASE, BEING ASSOCIATED WITH A WIDE SPECTRUM OF DISORDERS, INCLUDING ANXIETY DISORDERS, DEPRESSION, MIGRAINE, BIPOLAR, SCHIZOPHRENIA, EATING DISORDERS, AUTISM SPECTRUM DISORDERS, ATTENTION DEFICIT AND HYPERACTIVITY DISORDERS. THEREFORE, THIS WORK AIMED TO ANALYZE THE NEUROPSYCHOLOGICAL REPERCUSSIONS OF CELIAC DISEASE IN CHILDREN, ANALYZING THE MAIN DISORDERS TRIGGERED BY A GLUTEN-FREE DIET IN PEDIATRIC PATIENTS AND HOW THIS DISEASE INFLUENCES THE LIFESTYLE OF INFANTS. THEREFORE, IT IS CONCLUDED THAT CELIAC DISEASE IMPAIRS THE QUALITY OF LIFE, IN A WAY THAT REDUCES FUNCTIONALITY IN SOCIAL RELATIONSHIPS, IN EMOTIONAL LIFE AND PHYSICAL HEALTH, OBSERVING THE PREVALENCE OF PSYCHIATRIC DIAGNOSES PRESENT IN AT LEAST HALF OF THE CASES ANALYZED FOR THE PRESENT STUDY. THEN, THE INCREASE OF THE RATE OF EMOTIONAL AND BEHAVIORAL PROBLEMS IN CHILDREN AND ADOLESCENTS WITH CELIAC DISEASE EMPHASIZES THE IMPORTANCE OF EARLY DETECTION OF MENTAL HEALTH PROBLEMS IN THESE CHILDREN. IN ORDER TO FULFILL THE OBJECTIVES RAISED AND ANSWER THE RESEARCH DILEMMA, AN INTEGRATIVE LITERATURE REVIEW WAS USED AS A TOOL, WHICH WAS SUPPORTED BY INFORMATION TAKEN FROM THE VIRTUAL HEALTH LIBRARY (VHL), PUBMED, SCIENTIFIC ELECTRONIC DATABASES LIBRARY ONLINE (SCIELO) AND GOOGLE SCHOLAR.
Referências
ADDOLORATO, G. Anxiety but not depression decreases in coeliac patients after one-year
gluten-free diet: a longitudinal study. Scandinavian journal of gastroenterology, v. 36, n. 5,
p. 502-506, 2001.
AL NOFAIE, Norah D.; AL AHMADI, Jawaher R.; SAADAH, Omar I. Health related quality
of life among Saudi children and adolescents with celiac disease. Saudi journal of
gastroenterology: official journal of the Saudi Gastroenterology Association, v. 26, n. 1, p.
, 2020.
ALKHAYYAT, Motasem et al. Epidemiology and risk of psychiatric disorders among patients
with celiac disease: A populationâ€based national study. Journal of Gastroenterology and
Hepatology, 2021.
BATISTA, Icaro Camargo et al. Autism spectrum disorder and celiac disease: no evidence for
a link. Arquivos de Neuro-psiquiatria, v. 70, p. 28-33, 2012.
BUIE, Timothy et al. Evaluation, diagnosis, and treatment of gastrointestinal disorders in
individuals with ASDs: a consensus report. Pediatrics, v. 125, n. Supplement 1, p. S1-S18,
BUTWICKA, Agnieszka et al. Celiac disease is associated with childhood psychiatric
disorders: a population-based study. The Journal of pediatrics, v. 184, p. 87-93. e1, 2017.
CASSOL, Clarissa Araujo et al. Perfil clÃnico dos membros da associação dos celÃacos do
Brasil: regional de Santa Catarina (ACELBRA-SC). Arquivos de Gastroenterologia, v. 44, p.
-265, 2007.
CHELLAN, Deepak et al. Effect of glutenâ€free diet and compliance on quality of life in
pediatric celiac disease patients. JGH Open, v. 3, n. 5, p. 388-393, 2019.
COBURN, Shayna et al. Mental health disorders and psychosocial distress in pediatric celiac
disease. Journal of pediatric gastroenterology and nutrition, v. 70, n. 5, p. 608-614, 2020.
DEHBOZORGI, Mahshid et al. Clinical manifestations and associated disorders in children
with celiac disease in southern Iran. BMC pediatrics, v. 20, p. 1-7, 2020.
DOS SANTOS, Andressa Singolani; RIBEIRO, Cilene da Silva Gomes. Percepções de doentes
celÃacos sobre as consequências clÃnicas e sociais de um possÃvel diagnóstico tardio na doença
celÃaca. DEMETRA: Alimentação, Nutrição & Saúde, v. 14, p. 33310, 2019.
ESENYEL, Selcen; UNAL, Fatih; VURAL, Pinar. Depression and anxiety in child and
adolescents with follow-up celiac disease and in their families. The Turkish journal of
gastroenterology: the official journal of Turkish Society of Gastroenterology, v. 25, n. 4,
p. 381-385, 2014.
FERA, Tiziana et al. Affective disorders and quality of life in adult coeliac disease patients on
a gluten-free diet. European journal of gastroenterology & hepatology, v. 15, n. 12, p. 1287-
, 2003.
GALVÃO, LÃvia Carvalho et al. Apresentação clÃnica de doença celÃaca em crianças durante
dois perÃodos, em serviço universitário especializado. Arquivos de Gastroenterologia, v. 41,
p. 234-238, 2004.
GARG, Anu; GUPTA, Rajkumar. Predictors of compliance to gluten-free diet in children with
celiac disease. International scholarly research notices, v. 2014, 2014.
GIANNAKOPOULOS, Georgios et al. Child and Parent Mental Health Problems in Pediatric
Celiac Disease: A Prospective Study. Journal of pediatric gastroenterology and nutrition,
v. 71, n. 3, p. 315-320, 2020.
MAZZONE, Luigi et al. Compliant gluten-free children with celiac disease: an evaluation of
psychological distress. BMC pediatrics, v. 11, n. 1, p. 1-6, 2011.
NACINOVICH, Renata et al. Anorexia nervosa of the restrictive type and celiac disease in
adolescence. Neuropsychiatric disease and treatment, v. 13, p. 1211, 2017.
PATTON, Tiffany et al. Pediatric celiac disease and eosinophilic esophagitis: outcome of
dietary therapy. Journal of pediatric gastroenterology and nutrition, v. 69, n. 2, p. e43-e48,
PIMENTA-MARTINS, Ana; PINTO, Elisabete; GOMES, Ana MP. Perceção do estado de
saúde e da qualidade de vida numa amostra de celÃacos portugueses. GE Jornal Português de
Gastrenterologia, v. 21, n. 3, p. 109-116, 2014.
RASHID, Mohsin et al. Celiac disease: evaluation of the diagnosis and dietary compliance in
Canadian children. Pediatrics, v. 116, n. 6, p. e754-e759, 2005.
RICCA, Valdo et al. Anorexia nervosa and celiac disease: two case reports. International
Journal of Eating Disorders, v. 27, n. 1, p. 119-122, 2000.
SANCHEZ-VILLEGAS, Almudena et al. Long chain omega-3 fatty acids intake, fish
consumption and mental disorders in the SUN cohort study. European journal of nutrition,
v. 46, n. 6, p. 337-346, 2007.
SEL, Çiğdem Genç et al. Neurological manifestations of atypical celiac disease in
childhood. Acta Neurologica Belgica, v. 117, n. 3, p. 719-727, 2017.
