ANALYSIS OF THE EFFICACY OF 430 NM LED IN REDUCING BACTERIAL CONTAMINATION IN RENAL SCAFFOLD SLICES
Palavras-chave:
Phototherapy, Urology, Sterilization, LED, Bacterial inactivationResumo
Objective: This study aims to review the existing literature on the development and applications of 430 nm LED in bacterial inactivation in renal tissue scaffold slices, emphasizing its potential for clinical applicability. Methodology: A literature search was conducted in the PubMed database in August 2024, using the descriptors "phototherapy," "urology," "sterilization," or "bacterial inactivation," according to DeCS/BVS. Only original articles published between 2020 and 2024, available in English or Portuguese and open access, that directly addressed the topic were included. Non-original studies that dealt only with LEDs of wavelengths other than blue light were excluded. Results: The LED has proven to be a promising alternative to the widespread use of antibiotics, which contributes to bacterial resistance. However, challenges remain. Conclusion: The use of LED technology has shown to be effective, but further research is required to refine and optimize its application.
Referências
EL-GENDY, A O. et al. Studying the viability and growth kinetics of vancomycin-resistant Enterococcus faecalis V583 following femtosecond laser irradiation (420–465 nm). Lasers in Medical Science, v. 39, n. 1, p. 144, 2024.
HADI, J.; WU, S.; BRIGHTWELL, G. Antimicrobial blue light versus pathogenic bacteria: mechanism, application in the food industry, hurdle technologies and potential resistance. Foods, v. 9, n. 12, p. 1895, 2020.
HASENLEITNER, M.; PLAETZER, K. In the right light: Photodynamic inactivation of microorganisms using a LED-based illumination device tailored for the antimicrobial application. Antibiotics, v. 9, n. 1, p. 13, 2019.
IBRAHIM, R. A. et al. Antimicrobial Effect Of Diode Laser With Curcumin Nanoparticles Against Enterococcus Faecalis.(In Vitro Study). Journal of Pharmaceutical Negative Results, p. 2876-2886, 2023.
JOHNSON, R J.; FEEHALLY, J; FLOEGE, J. Nefrologia Clínica: abordagem abrangente. Elsevier Brasil, 2016.
MAGNI, G. et al. Blue-LED-light photobiomodulation of inflammatory responses and new tissue formation in mouse-skin wounds. Life, v. 12, n. 10, p. 1564, 2022.
SOARES, L.A.; NISHI, C.; WAGNER, H.L. Isolamento das bactérias causadoras de infecções urinárias e seu perfil de resistência aos antimicrobianos. Revista Brasileira de Medicina de Família e Comunidade, v. 2, n. 6, p. 84-92, 2006.
TEIXEIRA PEDROSO, J. et al. Effectiveness of the blue led in the photoinactivation of Staphylococcus aureus andStaphylococcus epidermidis in vitro. 2022.
Terminologia Básica em Saúde. Brasília, Centro de Documentação do Ministério da Saúde, 1983. (Série B: textos básicos de saúde n. 4)
Valles, R, Carmelo R. Photoeradication of Pathogens Through the Irradiation of Multifrequency Interfering Light-waves (MIL). Proceedings http://ceur-ws. org ISSN, v. 1613, p. 0073, 2022.
WANG, D. et al. Phototherapy and optical waveguides for the treatment of infection. Advanced drug delivery reviews, v. 179, p. 114036, 2021.
WOŹNIAK, A et al. Priming effect with photoinactivation against extensively drug-resistant Enterobacter cloacae and Klebsiella pneumoniae. Journal of Photochemistry and Photobiology B: Biology, v. 235, p. 112554, 2022.
YANG, W. et al. Photodynamic inactivation using natural bioactive compound prevents and disrupts the biofilm produced by Staphylococcus saprophyticus. Molecules, v. 26, n. 16, p. 4713, 2021.