ESSENTIAL OILS AND ISOLATED COMPOUNDS WITH ANTIBACTERIAL EFFECT

Abstract

IT IS REMARKABLE THAT ESSENTIAL OILS AND ISOLATED VOLATILE COMPOUNDS HAVE BIOLOGICAL ACTIVITIES WITH HIGH PHARMACEUTICAL, BIOCHEMICAL, BIOTECHNOLOGICAL AND AGRICULTURAL POTENTIAL. THIS STUDY AIMED TO EVALUATE ESSENTIAL OILS AND VOLATILE COMPOUNDS ISOLATED ON GROUPS OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA, VERIFYING THEIR BACTERICIDAL EFFECT. THE ESSENTIAL OILS OF MYROCARPUS FASTIGIATUS AND CYMBOPOGON WINTERIANUS, AND THE ISOLATED COMPOUNDS ALDEHYDE C:8, CINNAMALDEHYDE, α-IONONE AND HEXYL CINNAMIC ALDEHYDE WERE OBTAINED AND DONATED BY THE LABORATORY OF ORGANIC CHEMISTRY AND NATURAL PRODUCTS OF THE JATA� FEDERAL UNIVERSITY, GOI�S, BRAZIL . THE ANTIBACTERIAL ASSAY WAS PERFORMED USING THE PAPER DISK DIFFUSION METHOD AND THE INHIBITION HALO DETERMINED IN MILLIMETERS (MM) FOR ESCHERICHIA COLI, STAPHYLOCOCCUS AUREUS, SALMONELLA SEROVAR THYPHYMURIUM AND SEROVAR ENTERITIDIS, AND ENTEROCOCCUS FAECALIS. THE ESSENTIAL OILS SHOWED GOOD ANTIBACTERIAL ACTION, ALTHOUGH THE ISOLATED COMPOUNDS SHOWED GREATER BACTERICIDAL APTITUDE ON MOST TESTED BACTERIA. SALMONELLA SEROVAR THYPHYMURIUM AND SEROVAR ENTERITIDIS DEMONSTRATE RESISTANCE TO ESSENTIAL OILS AND ISOLATED COMPOUNDS. HOWEVER, THE OTHER BACTERIAL STRAINS SHOWED SENSITIVITY TO THE COMPLEX GROUPS OF PHYTOMOLECULES VERIFIED IN THIS STUDY. IT IS CONCLUDED THAT BOTH THE ESSENTIAL OILS AND THE ISOLATED VOLATILE COMPOUNDS TESTED, HAVE POTENTIAL PHARMACEUTICAL AND BIOLOGICAL USE FOR THE STRAINS EVALUATED.