FLORAL EXTRACT OF TIBOUCHINA GRANULOSA (DESR.) COGN. PHYTOCHEMISTRY PROSPECTION, AND ANTIBACTERIAL ACTIVITY

Abstract

TIBOUCHINA GRANULOSA IS A SPECIES THAT BLOOMS ANNUALLY IN SEVERAL REGIONS OF BRAZIL. THIS SPECIES IS STILL LITTLE EXPLORED IN TERMS OF PHYTOCOMPOUNDS IN ALL ORGANS OF THIS PLANT, ESPECIALLY THE FLORAL ORGAN. FLOWERS OF T. GRANULOSA WERE COLLECTED IN THE MUNICIPALITY OF RIO VERDE, GOI�S, BRAZIL, IN 2021. THE HYDROETHANOLIC FLORAL EXTRACT WAS PREPARED BY MACERATION AND QUALITATIVE PHYTOCHEMICAL (COLORIMETRIC REACTIONS AND SALT FORMATION) AND ANTIBACTERIAL ANALYZES PERFORMED AND THE RESULTS EXPRESSED IN MILLIMETERS OF INHIBITION AT DIFFERENT CONCENTRATIONS IN MG ML^-1. SEVERAL PHYTOCHEMICAL CLASSES WERE OBSERVED WITH POSITIVE RESULTS, ESPECIALLY FOR ALKALOIDS, PHENOLICS, OXYLATES, SAPONINS, CARBOHYDRATES AND TANNINS. AS FOR THE BACTERIAL ASSAY, POTENTIAL ANTIBACTERIAL ACTIVITY WAS OBSERVED FOR ALL BACTERIAL STRAINS TESTED, EXCEPT FOR SALMONELLA SEROVAR THYPHYMURIUM AND SEROVAR ENTERITIDIS. EXPRESSIVE INHIBITIONS WERE OBSERVED FOR ENTEROCOCCUS FAECALIS > PSEUDOMONAS AERUGINOSA > STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI AT THE HIGHEST CONCENTRATIONS BETWEEN 100-50 MG ML^-1. THE FLORAL EXTRACT OF TIBOUCHINA GRANULOSA SHOWED PHYTOTHERAPEUTIC POTENTIAL WITH THE PRESENCE OF SEVERAL PHYTOCHEMICAL GROUPS AND EXPRESSIVE ANTIBACTERIAL ACTIVITY.