RELAÇO DOS TRANSTORNOS DE HUMOR COM A DOENÇA DE HUNTINGTON

Autores

  • Beatriz Jorge Macedo de Machado
  • Camylla Borba de Sousa
  • Giovana Almeida Pultrini de Oliveira
  • Paula Gabriella Pereira Brandão
  • Samuel Di Salvatore
  • George Martins da Silva Jr

Palavras-chave:

Doença de Huntington. Transtornos de humor. Alterações psiquiátricas.

Resumo

A DOEN�A DE HUNTINGTON � UMA DOEN�A HEREDIT�RIA QUE PROVOCA A DEGENERA��O PROGRESSIVA DE C�LULAS NERVOSAS DO C�REBRO. DESCRITO PELO M�DICO NORTE-AMERICANO GEORGE HUNTINGTON EM 1872, O DIST�RBIO TEM SIDO AMPLAMENTE ESTUDADO NAS �LTIMAS D�CADAS. FOI INCLUSIVE EM 1993, POUCO MAIS DE CEM ANOS APÓS O PRIMEIRO CASO OFICIAL DA DOEN�A, QUE OS CIENTISTAS DESCOBRIRAM O GENE CAUSADOR DA AFEC��O - LOCALIZADO NO CROMOSSOMO 4. OS SINAIS E SINTOMAS CARACTER�STICOS DA DOEN�A DE HUNTINGTON SURGEM EM DECORR�NCIA DA PERDA PROGRESSIVA DE C�LULAS NERVOSAS QUE FICAM EM UMA PARTE ESPEC�FICA DO C�REBRO, OS G�NGLIOS DE BASE. APESAR DE V�RIOS ESTUDOS ACERCA DO TEMA, NÃO SE SABE AO CERTO COMO AS RELA��ES ANTERIORMENTE PROPOSTAS REALMENTE INTERFEREM NA MANIFESTA��O DOEN�A.  DESSA FORMA, O OBJETIVO DESTE TRABALHO � PESQUISAR UMA ASSOCIAÇÃO DA DOEN�A DE HUNTINGTON COM OS DIVERSOS TRANSTORNOS DE HUMOR NAS FASES PR�-CL�NICA, CL�NICA E PÓS-CL�NICA. PARA REALIZAR O TRABALHO, OPTOU-SE POR UMA REVISÃO INTEGRATIVA DE LITERATURA QUE ENGLOBA 20 ARTIGOS SELECIONADOS NA INTEGRA ENTRE OS ANOS DE 2006 E 2018 QUE ABORDAM A DOEN�A DE HUNTINGTON COMO TEMA PRINCIPAL. ASSIM, ENCONTRAMOS UMA DISCRETA, MAS CONSISTENTE RELAÇÃO ENTRE A DOEN�A E OS TRANSTORNOS DE HUMOR, AINDA PESQUISAMOS A LIGA��O DESSA ENFERMIDADE COM A ALTERA��O DA SAÚDE FAMILIAR, PRINCIPALMENTE A SAÚDE MENTAL.

Referências

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Publicado

2022-04-22

Edição

Seção

XV Mostra de Saúde - 10 anos do Curso de Medicina