HEMODYNAMIC AND STRUCTURAL ALTERATIONS OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH MORBID OBESITY: A LITERATURE REVIEW

Autores

  • Daniella Vallim Machado Universidade Evangélica de Goiás-UniEVANGÉLICA
  • Bruna Martins Rodrigues Silva Universidade Evangélica de Goiás-UniEVANGÉLICA
  • Antonio Moraes Faria Neto Universidade Evangélica de Goiás-UniEVANGÉLICA
  • Ananda Camille Silva Oliveira Universidade Evangélica de Goiás-UniEVANGÉLICA
  • Luís Vicente Franco De Oliveira Universidade Evangélica de Goiás-UniEVANGÉLICA

Palavras-chave:

obesity, cardiovascular disease, hemodynamics

Resumo

Introduction: Obesity, defined as a Body Mass Index (BMI) equal to or greater than 30, is a critical factor for cardiovascular health, manifesting itself in three distinct degrees. Objective: The objective of this review was to explore the cardiovascular changes associated with obesity and their implications for health. Method: Using databases such as PubMed and the Virtual Health Library (BVS), articles published between 2019 and 2024 were selected, focusing on "cardiovascular disease," "obesity," and "hemodynamics." The method involved filtering relevant studies, resulting in 11 articles addressing relevant issues regarding the cardiovascular effects of obesity. Results: The results showed that obesity induces significant hemodynamic changes, such as left ventricular remodeling and right ventricular dysfunction, and contributes to chronic inflammation and cardiac fibrosis. It was also observed that, paradoxically, individuals with moderate obesity may have a better cardiovascular prognosis compared to normal-weight individuals with heart failure. Conclusion: In conclusion, a multifaceted approach to the treatment of obesity, including lifestyle changes, pharmacological therapies, and bariatric surgery, may potentially reverse or mitigate the adverse cardiovascular changes associated with this condition.

Referências

Wanderley EN, Ferreira VA. Obesity: a plural perspective. Collective Health Science, 2010.

Ministry of Health [https://bvsms.saude.gov.br/11-10-dia-nacional-de- prevencao- daobesidade/#:~:text=The%20severity%20of%20obesity%20is,in%20which

%20BMI%20exceeds%2040]. 11/10 – National Obesity Prevention Day [accessed on 11 Sep 2024]. Available at: https://bvsms.saude.gov.br.

Bittencourt JC, Scheinbein GHA, Junior WCO, Bassi RL, Moura LB, Correa ALD, et al. Arterial stiffness indices, pulse wave velocity and central systolic blood pressure, are able to discriminate between obese and non-obese children. European Journal of Pediatrics, 2023.

Talib A, Roebroek YGM, Paulus GF, Loo KV, Winkes B, Bouvy ND, et al. Left Ventricular Geometrical Changes in Severely Obese Adolescents: Prevalence, Determinants, and Clinical Implications. Pediatric Cardiology, 2021.

Gutiérrez-Cuevas J, Sandoval-Rodriguez A, Meza-Rios A, Monroy-Ramíre HC, Galicia-Moreno M, García-Bañuelos J, et al. Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge. Cells, 2021.

Harada T, Obokata M. Obesity-Related Heart Failure with Preserved Ejection Fraction Pathophysiology, Diagnosis, and Potential Therapies. Heart Failure Clin, 2020.

Aryee EK, Ozkan B, Ndumele CE. Heart Failure and Obesity: The Latest Pandemic. Progress in Cardiovascular Diseases, 2023.

Preda A, Carbone F, Tirandi A, Montecucco F, Liberale L. Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management. Reviews in Endocrine and Metabolic Disorders, 2023.

Ma JI, Zern EK, Parekh JK, Owunna N, Jiang N, Wang D, et al. Obesity Modifies Clinical Outcomes of Right Ventricular Dysfunction. Circ Heart Fail, 2023.

Mandry D, Girerd N, Lamiral Z, Huttin O, Filippetti L, Micard E, et al. Arterial and Cardiac Remodeling Associated With Extra Weight Gain in an Isolated Abdominal Obesity Cohort. Frontiers in Cardiovascular Medicine, 2021.

Ozkan B, Ndumele CE. Exploring the Mechanistic Link Between Obesity and Heart Failure. Current Diabetes Reports, 2023.

Chen HHL, Bhat A, Gan GCH, Khanna S, Ahlenstiel G, Negishi K, et al. The impact of body mass index on cardiac structure and function in a cohort of obese patients without traditional cardiovascular risk factors. International Journal of Cardiology Cardiovascular Risk and Prevention, 2023.

Carbone S, Canada JM, Billingsley HE, Siddiqui MS, Elagizi A, Lavie CJ. Obesity paradox in cardiovascular disease: where do we stand? Vascular Health and Risk Management, 2019.

Downloads

Publicado

2025-08-27

Como Citar

Machado, D. V., Silva, B. M. R., Neto, A. M. F., Oliveira, A. C. S., & Oliveira, L. V. F. D. (2025). HEMODYNAMIC AND STRUCTURAL ALTERATIONS OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH MORBID OBESITY: A LITERATURE REVIEW. CIPEEX, 5(2), 1–5. Recuperado de https://anais.unievangelica.edu.br/index.php/CIPEEX/article/view/13134

Edição

Seção

ANAIS DO CIPEEX