EVALUATION OF THE ANTIFUNGAL ACTIVITY OF HEXANIC AND METHANOLIC EXTRACTS OF PURPLE IPÊ (HANDROANTHUS IMPETIGINOSUS) AGAINST CANDIDA ALBICANS AND ASPERGILLUS BRASILIENSIS

Autores

  • Bianca Rafaela de Sousa Sá Universidade Evangélica de Goiás - UniEVANGÉLICA
  • Anna Victória Gonçalves Martins Universidade Evangélica de Goiás - UniEVANGÉLICA
  • Rafaella Yokota Guedes Universidade Evangélica de Goiás - UniEVANGÉLICA
  • Karine Harumi de Castro Shimazaki Universidade Evangélica de Goiás - UniEVANGÉLICA

Palavras-chave:

purple ipê, Tenebrio molitor, antifungal activity

Resumo

Purple Ipê (Handroantus impetiginosus) is widely known for its phytotherapeutic properties and for the treatment of various pathologies, despite the lack of clarity about its medicinal mechanisms. This study investigated the antifungal activity of purple Ipê extracts using the Minimum Inhibitory Concentration (MIC) technique in vitro. The present study aimed to gather information on the feasible and cost-effective potential of new antifungal activities derived from purple Ipê extracts against Aspergillus brasiliensis and Candida albicans. However, no significant results were obtained, so there was no motivation to proceed with in vivo research on larvae. It is concluded that further studies should be conducted to explore alternative effective extraction methods of purple Ipê in combination with bioactive compounds to harness its therapeutic potential in clinical contexts.

Referências

QUING LIU, et al. Antibacterial and antifungal activities of spices. Int J Mol Sci, 18(6):1283, 2017. doi: 10.3390/ijms18061283.

SHARIFI-RAD, M. et al. Phytochemical analysis and biological investigation of Nepeta juncea benth. Different extracts. Plants Journal 2020, 9 (5), 646;doi.org/10.3390/plants9050646 .

PARAMESHWARI, K. K., & GIRIJA, C. S Antifungal effect of cinnamic acid characterized from the bark of Cinnamomum cassia against fluconazole-resistant Candida strains. Braz J Microbiol, 2024. doi: 10.1007/s42770-024-01469-w.

CORNELY, A. O. et al. Improving the outcome of fungal diseases - guiding experts and patients towards excellence. Wiley Online Library Journal.doi.org/10.1111/myc.12628 .

Medicinal and Aromatic Plants VII. Volume 28 of the series Biotechnology in Agriculture and Forestry pp 445-456; Available at: http://link.springer.com/chapter/10.1007%2F978-3-662-30369-6_27#page-. Accessed on Aug. 1, 2024.

BITTENCOURT, M. F., & SILVA, J. R. Antifungal activity of Handroanthus impetiginosus extracts against Candida species. Revista Brasileira de Farmacognosia, 30(2), 234-240, 2020.

Downloads

Publicado

2025-08-27

Como Citar

Sá, B. R. de S., Martins, A. V. G., Guedes, R. Y., & Shimazaki, K. H. de C. (2025). EVALUATION OF THE ANTIFUNGAL ACTIVITY OF HEXANIC AND METHANOLIC EXTRACTS OF PURPLE IPÊ (HANDROANTHUS IMPETIGINOSUS) AGAINST CANDIDA ALBICANS AND ASPERGILLUS BRASILIENSIS. CIPEEX, 5(2), 1–5. Recuperado de https://anais.unievangelica.edu.br/index.php/CIPEEX/article/view/12920

Edição

Seção

ANAIS DO CIPEEX